One of the longest trails in the Deep Creek Area, the trail runs 16.5 miles from the Campground to Newfound Gap Road, just south of the actual gap.  Deep Creek Trail offers access to a lot of backcountry campsites in the park, which can be reserved by calling (865) 436-1231.

From the campground, the first two miles will take you to the Indian Creek/Tom Branch Falls area.  Hiking north one more mile will bring you to the Loop Trail intersection.  From here, the Deep Creek trail stretches 4.3 miles, passing by Campsites #60, #59, and #58, before meeting Martins Gap Trail on the right.  Campsite #57 is at this trail intersection.  Also, at the Martins Gap Trail intersection, the Deep Creek Trail becomes a section of the Mountains-to-Sea Trail.

The trail continues up the mountain to Campsite #56, with the Pole Road Creek Trail branching off to the left a few feet above that.  Next, the Deep Creek/Mountains-to-Sea Trail continues 3.6 more miles, passing by Campsites #55 and #54 before coming to Campsite #53, where the trail meets the Fork Ridge Trail on the left.  Here, the Deep Creek Trail loses its Mountains-to-Sea Trail status and climbs another 3.9 miles to U.S. 441 (Newfound Gap Road).